TCR Recognition Peptidic Termini Play a Significant Role in
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منابع مشابه
Peptidic termini play a significant role in TCR recognition.
TCR recognition of class I MHC is dependent on the composition of the antigenic peptide and the MHC. Single amino acid substitutions in either the MHC or the peptide may dramatically alter recognition. While the major interactions between TCR and the peptide/MHC complex appear to be focused on the complementarity-determining region (CDR)3, it is also clear from the cocrystal structure of class ...
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